Clinicopathological Characteristics of Alpha-Fetoprotein-Producing Gastric Cancer

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Clinicopathological Characteristics of Alpha-Fetoprotein-Producing Gastric Cancer

PURPOSE α-fetoprotein (AFP)-producing gastric cancer is a rare tumor with high rates of liver metastasis and a poor prognosis. Many studies have been performed but there have been no comprehensive investigations of the clinicopathological and prognosis. MATERIALS AND METHODS Six hundred ninety four patients with gastric cancer who underwent a curative gastric resection in Hanyang University H...

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Novel characteristics of alpha-fetoprotein (AFP)-producing gastric cancer

Background Although serum AFP level is increased in the AFP-producing gastric cancer (GC) patient, AFP-producing GC may become recurrent without re-elevation of serum AFP level. Therefore, novel characteristics of AFP-producing GC such as other biomarkers are to be explored. Results 35 AFP-GC and 48 non-AFP-GC patients were included. Our present study revealed that blood type O (15 cases, 42....

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Clinicopathologic and prognostic characteristics of alpha-fetoprotein–producing gastric cancer

Alpha-fetoprotein-producing gastric cancer (AFPGC) accounts for 1.5%-7.1% of all gastric cancer cases. Compared with other types of gastric cancer, AFPGC is more aggressive and prone to liver and lymph node (LN) metastasis, with extremely poor prognosis. To improve understanding of AFPGC we reviewed a consecutive series of 82 AFPGC patients and investigated the prognostic factors. The incidence...

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Clinicopathological features of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation

AIM To investigate clinicopathological features of early stage gastric cancer with enteroblastic differentiation (GCED). METHODS We retrospectively investigated data on 6 cases of early stage GCED and 186 cases of early stage conventional gastric cancer (CGC: well or moderately differentiated adenocarcinoma) who underwent endoscopic submucosal dissection or endoscopic mucosal resection from S...

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A case of alpha-fetoprotein-producing gastric cancer.

INTRODUCTION A case of alpha-fetoprotein (AFP)-producing gastric cancer is described in a 57-year-old Chinese woman. CLINICAL PICTURE She presented with bleeding tendency and bone pain, and was found to have haematological evidence of disseminated intravascular coagulation and spinal metastasis. Her tumour markers, including AFP, Ca 19-9 and carcinoembryonic antigen (CEA) were elevated. In vi...

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ژورنال

عنوان ژورنال: Journal of Gastric Cancer

سال: 2011

ISSN: 2093-582X

DOI: 10.5230/jgc.2011.11.1.23